The FDA said it expects additional supply will be returning in the coming months.

Many of the ADHD medication shortages that have plagued the U.S. for the last two years have now been resolved, the Food and Drug Administration says. Yet some doctors and patients report they are still struggling to get prescriptions filled.

Dr. Royce Lee, a psychiatrist at the University of Chicago Medicine, said supply has gotten better but it’s still an issue for about a third of the patients he writes prescriptions for. This often means he still has to call around to pharmacies to see if they have the medications in stock, switch patients to different drugs, and deal with insurance companies to confirm coverage.

“I do see signs of the shortages easing up,” Lee said. “But there are still enough shortages that every day we’re having to put in a little bit of work for prescriptions that need to be changed or hunted down.”

Concerns raised as influencers promote pigment-injection procedure as latest cosmetic trend

From butter boards to viral dances, social media has spawned a host of fads, but experts have warned against the latest trend: eye-tattooing.

The procedure, known as keratopigmentation, is a recent development and can be used for therapeutic purposes to improve the appearance of eyes. This can include for people who have been left with scars on the transparent front part of the eye, known as the cornea, as a result of infection, disease or injury, or who have aniridia, a condition where the iris has not formed properly.

However, experts have raised concerns the procedure is becoming a popular aesthetic trend, with influencers posting TikTok videos of them undergoing surgery to permanently change their eye colour – often from brown to blue or green.

The bill, which would enhance penalties for people wearing masks while committing crimes, would also prohibit wearing masks in public for medical reasons.

Republican senators in North Carolina passed a bill Wednesday revoking a pandemic-era law allowing for masks to be worn in public for health concerns. 

The legislative proposal, dubbed the "Unmasking Mobs and Criminals" bill, was passed along party lines 30-15, despite outcries from some Senate Democrats to tweak it, allowing for the exception of using masks in public for anyone who feels their health or the health of their loved ones is compromised without them. 

In March a farm worker who reported no contact with sick or dead birds, but who was in contact with dairy cattle, began showing symptoms in the eye and samples were collected by the regional health department to test for potential influenza A. Experts have now confirmed the first case of highly pathogenic avian influenza transmission from a mammal (dairy cow) to a human.

Study identifies 618 proteins linked to 19 types of cancer, which could lead to much earlier detection

Proteins in the blood could warn people of cancer more than seven years before it is diagnosed, according to research.

Scientists at the University of Oxford studied blood samples from more than 44,000 people in the UK Biobank, including over 4,900 people who subsequently had a cancer diagnosis.

They compared the proteins of people who did and did not go on to be diagnosed with cancer and identified 618 proteins linked to 19 types of cancer, including colon, lung, non-Hodgkin lymphoma and liver.

The study, funded by Cancer Research UK and published in Nature Communications, also found 107 proteins associated with cancers diagnosed more than seven years after the patient’s blood sample was collected and 182 proteins that were strongly associated with a cancer diagnosis within three years.

​The authors concluded that some of these proteins could be used to detect cancer much earlier and potentially provide new treatment options, though further research was needed.​

New research being presented at the European Congress on Obesity (ECO) in Venice, Italy (12-15 May) has for the first time quantified the impact of different aspects of childhood obesity on long-term health and life expectancy.

The modeling by stradoo GmbH, a life sciences consultancy in Munich, Germany, presented by Dr. Urs Wiedemann, of stradoo, and colleagues at universities and hospitals in the UK, Netherlands, France, Sweden, Spain, U.S. and Germany, found that age of onset, severity and duration of obesity all take their toll on life expectancy.

The development of obesity at a very young age was found to have a particularly profound effect.

For example, a child living with severe obesity (BMI Z-score of 3.5) at the age of four, who doesn't subsequently lose weight, has a life expectancy of 39 years—about half of the average life expectancy.

Sales of raw milk appear to be on the rise, despite years of warnings about the health risks of drinking the unpasteurized products — and an outbreak of bird flu in dairy cows. 

Since March 25, when the bird flu virus was confirmed in U.S. cattle for the first time, weekly sales of raw cow’s milk have ticked up 21% to as much as 65% compared with the same periods a year ago, according to the market research firm NielsenIQ.

That runs counter to advice from the Food and Drug Administration and the Centers for Disease Control and Prevention, which calls raw milk one of the “riskiest” foods people can consume.

“Raw milk can be contaminated with harmful germs that can make you very sick,” the CDC says on its website.

As of Monday, at least 42 herds in nine states are known to have cows infected with the virus known as type A H5N1, federal officials said. 

The virus has been found in high levels in the raw milk of infected cows. Viral remnants have been found in samples of milk sold in grocery stores, but the FDA said those products are safe to consume because pasteurization has been confirmed to kill the virus.

Researchers say semaglutide, the active ingredient in Wegovy and Ozempic, could be biggest medical breakthrough since statins

A weight loss injection could reduce the risk of heart attacks and benefit the cardiovascular health of millions of adults across the UK, in what could be the largest medical breakthrough since statins, according to a study.

It found that participants taking the medication semaglutide, the active ingredient in brands including Wegovy and Ozempic, had a 20% lower risk of heart attack, stroke, or death due to cardiovascular disease.

The study, presented at the European Congress of Obesity (ECO) and led by researchers at University College London, also found that semaglutide brought about cardiovascular benefits for its participants, regardless of their starting weight or the amount of weight that they had lost. It suggests that those with mild obesity or who have lost only a small amount of weight could have an improved cardiovascular outcome.

Common infections will kill millions if drug resistance through misuse of antibiotics is not curbed, says England’s ex-chief medical officer

The Covid-19 pandemic will “look minor” compared with what humanity faces from the growing number of superbugs resistant to current drugs, Prof Dame Sally Davies, England’s former chief medical officer, has warned.

Davies, who is now the UK’s special envoy on antimicrobial resistance (AMR), lost her goddaughter two years ago to an infection that could not be treated.

She paints a bleak picture of what could happen if the world fails to tackle the problem within the next decade, warning that the issue is “more acute” than climate change. Drug-resistant infections already kill at least 1.2 million people a year.

“It looks like a lot of people with untreatable infections, and we would have to move to isolating people who were untreatable in order not to infect their families and communities. So it’s a really disastrous picture. It would make some of Covid look minor,” said Davies, who is also the first female master of Trinity College, Cambridge.

Finding that clearance of fluid in mice brains is lower in sleep and anaesthesia runs counter to dominant view in neuroscience

The restorative effect of a good night’s rest is widely recognised and the popular scientific explanation has been that the brain washes out toxins during sleep.

However, new findings suggest this theory, which has become a dominant view in neuroscience, could be wrong. The study found that the clearance and movement of fluid in the brains of mice was, in fact, markedly reduced during sleep and anaesthesia.

“It sounded like a Nobel prize-winning idea,” said Prof Nick Franks, a professor of biophysics and anaesthetics at Imperial College London, and co-lead of the study.

“If you are sleep-deprived, countless things go wrong – you don’t remember things clearly, hand-eye coordination is poor,” he added. “The idea that your brain is doing this basic housekeeping during sleep just seems to make sense.”

However, there was only indirect evidence that the brain’s waste-removal system ramps up activity during sleep, Franks said.

In the latest study, published in the journal Nature Neuroscience, researchers used a fluorescent dye to study the brains of mice. This allowed them to see how quickly the dye moved from fluid-filled cavities, called the ventricles, to other brain regions and enabled them to measure the rate of clearance of the dye from the brain directly.

The variant, called KP.2, now makes up the largest share of new infections in the U.S.

Disease experts anticipate a small uptick in Covid cases this summer, as a new variant spreads. 

The KP.2 variant represents 28% of Covid infections in the U.S., up from just 6% in mid-April, according to data released Friday by the Centers for Disease Control and Prevention. 

KP.2 became dominant at the end of April — meaning it accounts for the largest share of new cases — outpacing the JN.1 variant, which took over in the winter.

The first recipient of a genetically modified pig kidney transplant has died nearly two months after he underwent the procedure, his family and the hospital that performed the surgery said Saturday.

Richard “Rick” Slayman had the transplant at Massachusetts General Hospital in March at the age of 62. Surgeons said they believed the pig kidney would last for at least two years. 

The transplant team at Massachusetts General Hospital said in a statement it was deeply saddened by Slayman’s passing and offered condolences to his family. They said they didn’t have any indication that he died as a result of the transplant.

cross-posted from: https://lemmy.ml/post/15508914

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