Monitor is plugged into graphics card.
For those playing at home I have uninstalled, reinstalled, verified integrity of files, tried all combinations of running steam and dishonored as admin, there are no events in the event viewer, I have disabled onboard graphics, I tried running it off of a different hard drive, I tried starting it in windowed mode, I've tried compatibility modes for win 7 and 8, I've updated my graphics card driver, and there are no windows updates to apply.
I'm basically out of options over here. Looks like I don't get to play this game.
Looking at the community page there are definitely other people with the same or similar issues. No unique solutions though. Just the things I've already tried (which I list in a different comment).
This is so depressing.