Generally good, but fairly troublesome. I dualboot Pop_OS!, and the install was a nightmare. The live USB wouldn't boot until I unplugged every USB device. Once it started, I could plug them back in. Then, when actually installing, the info about the various partitions I would need was apparently pretty out of date (recommend partition sizes were way off).
Once installed, though, it's been really nice, albeit a fair bit more complicated. The only real issue I've had so far is that, in Unity games run through wine, video streamed in-game won't play.
If you're referring to the USB thing, I also tried booting Memtest86, GParted and Ubuntu to test, and all of them booted from a live USB without me having to unplug everything. That was totally unique to Pop_OS.
As for the proton, I'll try that fork. I did try a couple forks, though the latest Wine-GE is the only one I can think of the name of.
Edit: I'm using Lutris, and Wine-GE is the non-steam equivalent of Proton-GE, so... whomp whomp I guess