You need to use lutris 7.2-2 for the wine thingy. But if you want to use the latest wine, you can do these steps:
- select your game in lutris
- in the dropdown below (the wine glass icon), click Wine configuration
- there will be a popup, in the application scroll sideways until you get RDR2.exe
- click the rdr2.exe once
- then click Libraries
- there's going to be an entry called
vulkan-1 (native) - click it once, and then click remove
- then click OK button on the bottom
That's it!