According to the manual it is required to use both.
this post was submitted on 02 Sep 2023
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My guess with that TDP is yes. Iirc it's about 100W per connector.
I ran similar dual processors, each with a single x4 connector, while waiting for a conversion kit to turn one of my PCIe connectors into another set of plugs. It ran fine, but it's not officially recommended by my motherboard vendor, and I probably wouldn't have done it long-term. All that is to say that YMMV.