During my graduate research, our lab space was next to the cell modeling department and I would catch a talk here or there. Always found it a super interesting approach because it really tries to make sense of what we've learned from traditional biology and generates really nice hypotheses/theories for testing out in biological models. I also love how you can apply so much abstract mathematics to biological systems for biologically meaningful findings. Most of these types of cell modeling papers go above my head, but I still really appreciate them from outside.