this post was submitted on 07 Aug 2024
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[–] Nougat@fedia.io 14 points 3 months ago (2 children)

It's obviously going to be the next annual vaccination, like influenza has already been. I'm waiting for the next formulation to become available before I get my sixth round.

[–] mox@lemmy.sdf.org 17 points 3 months ago (2 children)

Annual isn't enough.

Pooled estimates of VE of a primary vaccination cycle against laboratory-confirmed Omicron infection and symptomatic disease were both lower than 20% at 6 months from last dose administration. Booster doses restored VE to levels comparable to those acquired soon after the administration of the primary cycle. However, 9 months after booster administration, VE against Omicron was lower than 30% against laboratory-confirmed infection and symptomatic disease.

https://pubmed.ncbi.nlm.nih.gov/37133863/

[–] Nougat@fedia.io 5 points 3 months ago

Oh, yeah, I meant to type "at least" annual. Apparently, my brain thinking about typing that was enough.

[–] aramis87@fedia.io 4 points 3 months ago (1 children)

There's some early evidence that more traditional vaccines (like NovaVax) may create longer protection than the mRNA vaccines (which seem to have more robust but shorter-lasting protectection).

[–] mox@lemmy.sdf.org 4 points 3 months ago

Interesting. Can you link some details?

[–] BrightCandle@lemmy.world 4 points 3 months ago

So far we have had between 4 and 6 waves a year, each of which is from a different variant. A variant breaks out and within 2 months its infected almost everyone at which point it dies down to become part of the background infections and a new variant takes over. There just isn't enough time to make a vaccine and roll it out to deal with any of that problem. The vaccines that are getting rolled out now are for variant that disappeared 6 months ago. Nothing we do is going to be very effective against this until the vaccines are a lot more effective against potential future variants or we drastically reduce the number of hosts it gets to replicate in.