I absolutely love Hamilton's Commonwealth universe! Pandora's Star then Judas Unchained, then the void trilogy followed up by The Abyss Beyond Dreams. I've read all of them 3 times and thinking of doing a 4th round soon!
I've also seen House of Suns mentioned here a few times. It gets my vote for the exploration of deep time due to the speed limits of causality.
It takes an hour or two for me before they hit. Early on circa 2013-14 when I was discovering edibles trying to feel the high, I hate the whole chocolate bar! What an awesome experience.