Yeah. There is definitely several stories that could play out here, for both M’Benga and Chapel.
Continuity wise McCoy didn't join the Enterprise until after the first couple of episodes of TOS s1, Mark Piper was the CMO for those so there is definitely a thread they could pick on prior to Kirk taking command of the Enterprise.
For Chapel we know she gets engaged to Roger Korby at some point. Will be interesting to see how they move the character to line up with 'What Are Little Girls Made Of?'
TNG: 'Q Who'
DS9: 'In The Pale Moonlight'
Voyager: 'Scorpion'
Enterprise: 'Carbon Creek'
Discovery: 'Magic to Make the Sanest Man Go Mad' or 'Die Trying'
(I also have a soft spot for parts of Picard season 1)