Some games require more buttons than one of the included controllers (joycon) provide. So with the included ones that would make the game single player only. As a rule of thumb, any game where you can move in 3D requires both joycons.
Mario Kart is great. It can entertain for a long time if they like racing. The two joycons are sufficient for two players.
Here is the list of the best Switch games in general. Maybe something catches your fancy?