this post was submitted on 22 Oct 2024
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Genetic variants linked to ADHD and Parkinson's, Queensland led study on brain size finds (www.abc.net.au)
submitted 3 weeks ago by Deceptichum@quokk.au to c/world@quokk.au
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"Larger brain volumes tend to increase the risk of Parkinson’s disease later in life and smaller brain volumes tend to increase the risk of ADHD."

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[–] cuban_Pete@lemy.lol 8 points 3 weeks ago (1 children)

Have trouble thinking your whole life or have trouble thinking when old?

[–] Apytele@sh.itjust.works 11 points 3 weeks ago

I have adhd and I'd much rather have ADHD than Parkinsons. Trouble thinking doesn't cover it. It's a movement disorder that causes pain and 24/7 restlessness along with dementia. No thank you.

[–] Apytele@sh.itjust.works 7 points 3 weeks ago (1 children)

Makes sense, actually; dopamine is highly implicated in both disorders. ADHD responds to stimulants because they increase dopamine. Unfortunately they can also cause psychosis in large enough doses (common problem with meth and cocaine use). Antipsychotics, which reverse the psychosis... cause pseudoparkinsonianism, or drug-induced Parkinsons. Not sure exactly how this part of the puzzle fits in, but I've definitely seen some other puzzle pieces from that corner, to extend the metaphor.

[–] Pronell@lemmy.world 1 points 3 weeks ago* (last edited 3 weeks ago) (1 children)

Yup, I think tardive diskenesia is the same thing. If you've seen old videos from asylums where the patients are twitching rather violently, that's advanced tardive diskenesia.

More modern medicines don't cause it to be as pronounced but it's still an issue.

[–] Apytele@sh.itjust.works 2 points 3 weeks ago

I've actually both had it and treated my patients for it!

[–] Noodle07@lemmy.world 1 points 3 weeks ago

So I'm literally small brained? Dayum